A choir is singing out to help their choir-mate’s granddaughter.

Polperro Fishermen’s Choir will be raising funds for a charity researching a life-limiting neurological condition.

Reverse Rett was set up in 2010 to fund research into a cure for Rett Syndrome, which is caused by a genetic mutation mainly affecting little girls.

Lottie Lashbrooke, the six-year-old granddaughter of choir chairman David Lashbrooke, suffers from the condition.

Lottie is unable to say more than a few words and has great difficulty controlling her hands or concentrating. Many of those affected develop multiple disabilities and medical complexities.

David said: ‘Lottie is a very happy and loving little girl who likes music and enjoys coming to Cornwall.

‘The members of the choir were so moved by Lottie’s story that they voted unanimously to support the charity.’

The choir has the backing of its president, broadcaster and writer Richard Madeley, who said: ‘Having a daughter myself, I realise how devastating it must be to a family to receive a diagnosis of Rett Syndrome. The charity Reverse Rett gives them hope and I fully support the efforts of the choir to raise money for this important cause’.

Lottie’s mum Debbie said: ‘Lottie is the sweetest, funniest, most beautiful little girl imaginable and she is the heartbeat of our family.

‘What is truly amazing is that she manages all of this without being able to speak or operate her body properly.’

The choir is giving its final free open-air concert of the year on Polperro Fish Quay on Wednesday, August 23, when money will be collected for Reverse Rett and the British Heart Foundation.

Lottie’s grandad has promised to double all donations made to Reverse Rett.